Todd Mc Carthy of Variety criticized her break from the big screen but felt that, despite a performance of "tender feeling", "her natural vivaciousness and spontaneity are straightjacketed" by the film noir format.
Afterwards, Mc Adams starred with Tim Robbins and Michael Peña in the road trip comedy-drama The Lucky Ones, a story about three Iraq War soldiers on a brief road trip back in the United States.
In 2010, Mc Adams appeared in her first star vehicle, the comedy Morning Glory.
The Italian-Canadian co-production was filmed in Sicily when Mc Adams was 22 years old, and it marked her first time on an airplane.Mc Adams played Della Frye, an online reporter who investigates a possible conspiracy with Crowe's character, a veteran print journalist.while Sukhdev Sandhu of The Daily Telegraph noted that "Mc Adams, with her lively eyes and large, expressive forehead, holds her own against Crowe.She later parted ways with her publicist at the time, who had not informed her in advance."There were a lot of cooks in the kitchen, a lot of voices around me, and I wanted to step away so I could hear my own voice again", Mc Adams said in 2013.
In 2005, Mc Adams starred with Owen Wilson, Vince Vaughn and Bradley Cooper in the romantic comedy Wedding Crashers.